- A randomized controlled trial of 108 people with HIV-associated lipohypertrophy found that weekly Ozempic treatment for 32 weeks reversed biological age by an average of 3.1 years. - The study used epigenetic clocks to measure biological aging, showing the most pronounced anti-aging effects in the inflammatory system and brain, where aging was delayed by almost 5 years. - Researchers believe the anti-aging effects stem from semaglutide's ability to improve fat distribution and reduce inflammation, both major drivers of cellular aging. - While the study focused on a specific patient population, the biological pathways affected by semaglutide suggest similar anti-aging effects could occur in other populations.