The ability of red states to outright defy a Democratic federal government that followed the rules was quite limited. I don’t see defiance by blue states against a government that does not follow the rules going very far. It would be nice if states had enough autonomy in this context to act as a safety valve on federal power (and a lot closer to the original intent of the Constitution) but almost no one actually supports that as a matter of principle so both parties take turns attacking it when they control the federal government and now here we are…