If you’re on Android, go to settings and network, find and enable private dns mode using this host address

dns.adguard-dns.com

It should block the majority of ingame/inapp ads, etc

Edit: Minor Caveat. This isn’t fool proof nor is it 100% effective.

But takes you all of 30 seconds and does not require root permissions, side loaded apps, etc. Its all about the cost benefit ratios.