in mice.
Still promising, but you can almost always append “in mice” to these kinds of headlines.
And if you’re in the US you can append “only in rich people” as well.
Only rich people can rebuild and ride the titan submarine and recreate the view of the Titanic.
Of course, but they’ve also seen the effects in human tissue samples. Also this reference about already having used the inhibitor in human volunteers for muscle weakness shows good promise:
Blau added, “Phase 1 clinical trials of a 15-PGDH inhibitor for muscle weakness have shown that it is safe and active in healthy volunteers. Our hope is that a similar trial will be launched soon to test its effect in cartilage regeneration. …”
I sure could use some of that there cartilage. I feel it in me bones.
This is very interesting. I could have used this 10 years ago.
Inhibition of 15-hydroxy prostaglandin dehydrogenase promotes cartilage regeneration https://www.science.org/doi/10.1126/science.adx6649
Human cartilage samples taken from knee replacement surgeries also responded positively.
It’s always so bleak reading about this phase of clinical trials. Orthopaedic surgery is wildly brutal and these patients were 5-10 years away from being able to avoid the lifetime of trauma that comes with it. lt’s a complete roll of the chronological dice whether you’ll be the tissue sample that proves a 100% fatal cancer treatment works or the patient in a phase 3 trial with a 50% survival rate or the patient who gets the little beepboop thing that turns it into an inconvenience.
Give me the 15-PGDH inhibitor
